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. 2015 Aug 7;22(1):65. doi: 10.1186/s12929-015-0171-x

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© Huang et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Mouse protection elicited by rlipoA-RBD against lethal TcdA challenge. Panel a, BALB/c mice (10 mice per group) were challenged with a lethal dose of TcdA after three immunizations of either rlipoA-RBD or A-rRBD (0.3 and 3 ug). PBS served as the negative control. The final survival rates were reported. Panel b, BALB/c mice (10 mice per group) were challenged with a lethal dose of TcdA after three immunizations of either rlipoA-RBD (0.3 and 3 μg) or 30 μg of B-rRBD