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. Author manuscript; available in PMC: 2015 Aug 6.
Published in final edited form as: Arthritis Rheum. 2013 Dec;65(12):3228–3238. doi: 10.1002/art.38123

Figure 4.

Figure 4

Morphologic changes in the salivary glands of AAV5-Bmp6–treated mice. Changes in morphology and in protein expression or distribution were assessed by hematoxylin and eosin (H&E) or trichrome staining or immunofluorescence confocal imaging for aquaporin 5 (AQP-5). Each image is representative of 4 samples tested. No gross changes in morphology were observed with H&E staining. Trichrome staining revealed a redistribution of the extracellular matrix material in AAV5-Bmp6–treated mice compared with AAV5-GFP–treated controls. AQP-5 appeared to be less well defined on the apical surfaces in the AAV5-Bmp6–treated mice compared with the AAV5-GFP–treated mice. Original magnification × 40 (H&E) or × 100 (trichrome and AQP-5). See Figure 2 for other definitions.