Table 2.
Body Weight (g) and Relative AGDa of Offspring (PNDs 0 to 21) Stratified by Postnatal Expsoure Status.b
| End Point | TCC | ||
|---|---|---|---|
| Control | 0.2% w/w | 0.5% w/w | |
| Litter No. | 5 | 5 | 5 |
| Body weight | |||
| PND 0 | 5.67 ± 0.06 (30) | 5.71 ± 0.06 (30) | 5.66 ± 0.06 (30) |
| PND 3 | 9.19 ± 0.28 (30) | 7.72 ± 0.13 (27)c | 6.89 ± 0.25 (27)c,d |
| PND 6 | 14.23 ± 0.59 (30) | 8.67 ± 0.63 (27)c | ND |
| PND 9 | 21.46 ± 0.84 (30) | 12.06 ± 0.12 (17)c | ND |
| PND 21 | 55.59 ± 0.95 (30) | 29.55 (4)e | ND |
| Relative AGD | |||
| PND 3 | 0.92 ± 0.02 (30) | 1.02 ± 0.05 (27) | 0.92 ± 0.03 (27) |
| PND 6 | 1.03 ± 0.03 (30) | 1.00 ± 0.04 (27) | ND |
| PND 21 | 2.46 ± 0.03 (30) | 2.51 (4)e | ND |
Abbreviations: ANOVA, analysis of variance; AGD, anogenital distance; ND, no offspring survived on that specific PND; TCC, triclocarban; PND, postnatal day.
a Relative AGD: AGD/cube root of body weight on that specific PND.
b ANOVA, P < .05.
c Statistical significance compared to control.
d Statistical significance compared to control and 0.2% w/w groups on that specific PND.
e All the surviving offspring were raised in the same litter. Number in the parentheses indicates the total number of offspring surviving on that specific PND.