Table 4.
End Point | In Utero Status | ||
---|---|---|---|
Control | 0.2% w/w | 0.5% w/w | |
Litter No. | 5 | 5 | 5 |
Body weight, g | 181.33 ± 3.91 | 178.25 ± 3.21 | 180.49 ± 6.24 |
Relative organ weight | |||
Pituitary | 0.05 ± 0.00 | 0.05 ± 0.00 | 0.08 ± 0.01 |
Adrenal | 0.14 ± 0.01 | 0.14 ± 0.01 | 0.15 ± 0.01 |
Kidney | 3.57 ± 0.12 | 3.60 ± 0.03 | 3.61 ± 0.07 |
Liver | 37.58 ± 1.18 | 38.62 ± 0.88 | 39.86 ± 0.78 |
Spleen | 2.82 ± 0.03 | 2.80 ± 0.24 | 2.95 ± 0.11 |
Uterine horn | |||
Wet | 1.96 ± 0.20 | 2.28 ± 0.54 | 1.97 ± 0.29 |
Dry | 1.79 ± 0.16 | 1.86 ± 0.18 | 1.67 ± 0.17 |
Ovary | 0.57 ± 0.023 | 0.49 ± 0.04 | 0.50 ± 0.02 |
Abbreviation: PND, postnatal day.
a Offspring were terminated on estrus day prior to or shortly after PND 54; relative organ weight: organ weight (g) × 1000/body weight (g).