Table I.
A comparison of baseline patient and tumor characteristics according to the treatment cohort.
| Characteristic | No prior WBRT cohort 20 patients/21 cavities | Prior WBRT cohort 10 patients/11 cavities | p-value |
|---|---|---|---|
| Median age (range) | 70 (41-90) | 57 (24-71) | 0.006 |
| Male | 7 | 3 | 0.45 |
| Female | 13 | 7 | |
| NSCLC | 10 | 4 | 0.27 |
| Breast | 3 | 3 | |
| Other | 8 | 4 | |
| Frontal | 6 | 1 | 0.27 |
| Temporal | 2 | 3 | |
| Parietal | 4 | 4 | |
| Occipital | 1 | 1 | |
| Cerebellum | 7 | 1 | |
| Pre-op median tumor | 3.4 cm | 3.2 cm | 0.49 |
| Diameter (range) | (2.0-4.7) | (2.5-6.2) | |
| GTR | 17 | 6 | 0.70 |
| STR | 4 | 5 | |
| ECOG 0 | 3 | 2 | 0.73 |
| ECOG 1 | 17 | 8 | |
| RPA Class I | 7 | 3 | 0.78 |
| RPA Class II | 13 | 7 | |
| GPA 0-1 | 0 | 3 | 0.55 |
| GPA 1.5-2.5 | 17 | 6 | |
| GPA 3-4 | 3 | 1 |
WBRT refers to whole brain radiotherapy, RPA refers to the brain metastases recursive partioning analysis, GPA refers to the brain metastases graded prognostic analysis, NSCLC refers to non-small cell lung cancer.