Table 4. . Tacrolimus doses, trough concentrations and concomitant medication use.
| Median (IQR) or number with (%) | |
|---|---|
| Number of trough concentrations |
35,043 |
| Total daily dose (mg) |
6.0 (4–8) |
| Trough concentration (ng/ml) |
8.1 (6.1–10.1) |
| Trough dose-normalized (ng/ml per mg/day) |
1.38 (0.87–2.18) |
| Dosing interval: | |
| – Twice daily | 34,553 (98.6%) |
| – Once daily | 414 (1.2%) |
| – Three-times a day |
75 (0.2%) |
| Trough concentrations with ACE inhibitor |
4592 (13.1%) |
| Trough concentrations with calcium channel blocker |
14,002 (40.0%) |
| Trough concentrations with corticosteroids |
21,379 (61.0%) |
| Trough concentrations with antiviral drug | 19,658 (56.1%) |
IQR: Interquartile range.