Table 2.

Pre- to posttreatment histogram measurement change statistical analysis

Variable	Mean	SD	Median	Lower quartile	Upper quartile	Minimum	Maximum	P-value
Image mean	−12.911	14.699	−9.390	−18.962	−4.161	−46.373	1.459	0.0098
Image mode	−13.733	20.425	−9.167	−24.667	−4.333	−45.333	17.000	0.084
Image median	−12.367	14.358	−9.833	−18.333	0	−42.333	3.000	0.0195
Skewness	0.243	0.529	−0.024	−0.093	0.422	−0.292	1.204	0.625
Raw Integrated Density	−100783	77363	−71590	−163967	−48921	−244398	−3112	0.002

Note: P-values were calculated using the signed-rank test.