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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Exp Mol Pathol. 2015 Jun 14;99(1):109–115. doi: 10.1016/j.yexmp.2015.06.004

Fig. 5.

Fig. 5

Schematic diagram showing HIV induced alteration in biological membrane leading to LPA biosynthesis, and activating various kinase cascade and to NFκB activation and EMT related gene modulation. Inhibitors that block LPA pathway, signal transduction process and or NFκB activation could effectively block this pathway of EMT gene expression/modulation.