Fig 8. Analysis of pairwise per-site root mean square deviation (RMSD) between the echinoderm structures (1hlb, 1hlm) and the Ngb (1oj6) and Cygb (1urv) structures.

Colored blocks at the bottom indicate charged (red) and non-charged (black) residues. Gaps are shown in grey, and the proximal and distal histidines are shown in blue. Helix locations are annotated above, and names using standard conventions. Overall RMSD for each plot is computed as the mean of the squared contributions from each site, and is indicated by the dashed red line. The blue areas underneath indicate the confidence associated with each column in the multiple alignment, as outputted by StructAlign.