Table 2. The number of differentially methylated (DM) CpG sites among the 375,324 filtered-in CpG sites between the monozygotic (MZ) co-twins with the dual thresholds of absolute difference in the M-value (ΔM) and the False Discovery Rate (FDR)-adjusted P value.
Threshold | #1 (%) | #2 (%) | #3 (%) | #4 (%) | #5 a (%) | #6 (%) | #7 (%) | #8 (%) | #9 (%) | #10 (%) |
---|---|---|---|---|---|---|---|---|---|---|
|ΔM| > 1.0 & FDR-adjusted P value < 0.05 | 1,460 | 1,074 | 513 | 5,743 | 3,481 | 327 | 906 | 922 | 509 | 452 |
0.389% | 0.286% | 0.137% | 1.530% | 0.927% | 0.087% | 0.241% | 0.246% | 0.136% | 0.120% | |
|ΔM| > 1.0 & FDR-adjusted P value < 0.01 | 1,191 | 804 | 369 | 4,707 | 2,971 | 236 | 692 | 738 | 377 | 347 |
0.317% | 0.214% | 0.098% | 1.254% | 0.792% | 0.063% | 0.184% | 0.197% | 0.100% | 0.092% | |
|ΔM| > 1.0 & FDR-adjusted P value < 0.001 | 934 | 579 | 249 | 3,713 | 2,415 | 164 | 489 | 555 | 262 | 233 |
0.249% | 0.154% | 0.066% | 0.989% | 0.643% | 0.044% | 0.130% | 0.148% | 0.070% | 0.062% | |
|ΔM| > 1.0 & FDR-adjusted P value < 0.0001 | 755 | 451 | 191 | 3,042 | 1972 | 110 | 399 | 455 | 188 | 171 |
0.201% | 0.120% | 0.051% | 0.810% | 0.525% | 0.029% | 0.106% | 0.121% | 0.050% | 0.046% |
a: MZ 5A vs. MZ 5B_1st.