Skip to main content
. 2015 Aug 6;11(8):e1005077. doi: 10.1371/journal.ppat.1005077

Table 1. Regional distribution of PrPres and vacuolation in the brain of transgenic rabbits expressing ovine PrP challenged with LA21K fast prions.

Brain Regions PrPres deposits Spongiosis
Cortex +++ -
Hippocampus +++ +
Thalamus +++ ++
Cerebellum +/- +/-
Obex + +/-
Medulla oblongata + +

-: no staining, no vacuolation; +/-: low; +: moderate; ++: pronounced; +++, intense staining or spongiosis.