Table 1.
Diagnosis and treatment timeline
| Aug-12 | Feb-13 | May-13 | Jun-13 | Sep-13 | Nov-13 | Jan-14 | Feb-14 | Apr-14 | May-14 | Jun-14 |
|---|---|---|---|---|---|---|---|---|---|---|
| Diagnosed with CLL | FCR × 6 cycles | CT scan demonstrated recurrence | Rituximab and Bendamustine × 2 cycles | Ofatumumab × 5 cycles | R-EPOCH × 4 cycles | Richter confirmed. PET scan no response | R-ICE × 1 cycle; R-DHAC × 3 | PET scan without response | Ibrutinib 420 mg daily and Rituximab weekly × 5 | PET response – eligible for transplant |
CLL, chronic lymphocytic leukemia; FCR, fludarabine, cyclophosphamide, and rituximab.