Table 4.
Univariate | Multivariate‡ | ||||
---|---|---|---|---|---|
Outcome | N | RR (95% CI) | P | RR (95% CI) | P |
Overall Survival | |||||
no-EMD | 8983 | 1.00 | 0.73 | 1.00 | 0.91 |
EMD | 814 | 1.02 (9.03–1.11) | 1.00 (0.91–1.09) | ||
Leukemia Free Survival | |||||
no-EMD | 8877 | 1.00 | 0.58 | 1.00 | 0.74 |
EMD | 804 | 1.03 (0.94–1.12) | 0.98 (0.89–1.09) | ||
Treatment Related Mortality | |||||
no-EMD | 8877 | 1.00 | 0.05 | 1.00 | 0.23 |
EMD | 804 | 0.87 (0.76–1.00) | 0.92 (0.80–1.06) | ||
Relapse | |||||
no-EMD | 8877 | 1.00 | 0.01 | 1.00 | 0.62 |
EMD | 804 | 1.16 (1.03–1.30) | 1.03 (0.92–1.16) |
MVA model adjusted for: WBC at diagnosis, previous history of MDS, cytogenetic risk group, disease status prior to HSCT, duration of CR1, site of relapse for patients transplanted in >=CR2, time from diagnosis to HSCT, consolidation treatment, age group, conditioning regimen, type of donor, graft type, CMV serostatus, year of HSCT, GVHD prophylaxis.
DLI was excluded from model.