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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 May 19;8(8):683–692. doi: 10.1158/1940-6207.CAPR-15-0090

Figure 6.

Figure 6

CISH analysis indicates that IL-6 is not expressed locally in cribriform PIN/CIS lesions. IL-6 expression in the rat ventral prostate was only observed in infiltrating immune cells (arrowheads) in areas of acute inflammation (as evidenced by the dense infiltration of neutrophils, arrow) in E. coli-alone treated animals (A). IL-6 was not observed by CISH in cribriform PIN/CIS lesions in either PhIP (B) or PhIP+E. coli (C) treated rats. Single spots in the nucleus likely represent the genomic copy of IL-6.