Table 2. Comparison of complement components in the brain cortex at 24 hours after ROSC between the NT and HT groups.
C1q (pg/mg) | Bb (ng/mg) | MBL (μg/mg) | C3b (μg/mg) | C3a (ng/mg) | C5a (ng/mg) | |
---|---|---|---|---|---|---|
NT | 1.44±0.41 | 10.83±1.58 | 1.01±0.09 | 1.03±0.09 | 40.30±9.45 | 12.60±0.77 |
HT | 0.97±0.15* | 9.78±1.17 | 0.72±0.15* | 0.84±0.12* | 37.57±6.61 | 10.23±1.45* |
Abbreviations: HT, mild hypothermia; MBL, mannose-binding lectin; NT, normothermia; ROSC, restoration of spontaneous circulation.
The concentrations of complement components are expressed in pg/mg (C1q), μg/mg (MBL and C3b), and ng/mg (Bb, C3a and C5a) of total protein content.
*P<0.05 versus brain content in the NT group.