Table 2.
Odds ratios and 95% confidence intervals for adenoma according to quartile of 25-hydroxyvitamin D level
Quartile of serum 25(OH) D levels |
P for trend | ||||
Quartile1 | Quartile2 | Quartile3 | Quartile4 | ||
All patients | |||||
Median (ng/mL) | 10.33 | 14.25 | 17.91 | 24.21 | |
Case/control | 37/28 | 26/28 | 28/28 | 21/28 | |
Model 1 | 1.00 | 0.71 (0.35-1.45) | 0.73 (0.33-1.61) | 0.52 (0.23-1.20) | 0.15 |
Model 2 | 1.00 | 0.72 (0.31-1.66) | 0.73 (0.29-1.82) | 0.49 (0.19-1.27) | 0.16 |
Men | |||||
Median (ng/mL) | 11.08 | 14.6 | 17.65 | 22.66 | |
Case/control | 15/14 | 13/14 | 17/15 | 12/14 | |
Model 1 | 1.00 | 0.95 (0.35-2.57) | 1.10 (0.29-4.18) | 0.80 (0.25-2.60) | 0.74 |
Model 2 | 1.00 | 1.31 (0.36-4.82) | 1.26 (0.23-6.87) | 1.80 (0.40-8.12) | 0.46 |
Women | |||||
Median (ng/mL) | 9.48 | 13.53 | 18.4 | 25.42 | |
Case/control | 16/14 | 22/14 | 8/14 | 9/13 | |
Model 1 | 1.00 | 1.31 (0.53-3.24) | 0.51 (0.18-1.51) | 0.65 (0.20-2.14) | 0.16 |
Model 2 | 1.00 | 0.89 (0.26-3.10) | 0.54 (0.13-2.16) | 0.22 (0.04-1.15) | 0.05 |
Model 1 was adjusted for age (continuous). Model 2 was adjusted for the following covariates; men: age (years, continuous), body mass index (BMI) (kg/m2, 18.5- < 23, 23- < 25, > 25), alcohol drinking (nondrinker, past drinker, ≤ 1/mo, 2-4/mo, 2-3/wk, ≥ 4/wk), smoking status (never, 0- < 20, 20- < 30, > 30 pack-years of smoking), and folate intake (mcg/d, continuous); women: age (years, continuous), BMI (kg/m2, 18.5- < 23, 23- < 25, > 25), alcohol drinking (nondrinker, ever drinker), smoking status (never, ever smoker), folate intake (mcg/d, continuous), and menopausal status and hormone replacement use (premenopausal, postmenopausal without hormone replacement therapy, postmenopausal with hormone replacement therapy, postmenopausal with nonresponse about hormone replacement therapy use).