Table 5.
Chronic Liver Failure-Sequential Organ Failure Assessment score
Organ | Variabel | 0 | 1 | 2 | 3 | 4 |
Liver | Billirubin, μmol/L | < 20 μmol/L | ≥ 20 to < 34 μmol/L | ≥ 34 to < 103 μmol/L | ≥ 103 to < 205 μmol/L | > 205 μmol/L |
(mg/dL) | (-1.1) | (≥ 1.1 to < 1.9 ) | (≥ 1.9 to < 6.0) | (≥ 6.0 to < 11.9) | (> 11.9)1 | |
Kidney | Creatinine, μmol/L | < 106 μmol/L | ≥ 106 to < 177 μmol/L | ≥ 177 to < 309 μmol/L | ≥ 309 to < 442 μmol/L | > 442 μmol/L |
(mg/dL) | (< 1.2) | (≥ 1.2 to < 2.0) | (≥ 1.2 to < 3.5)1 | (≥ 3.5 to < 5)1 | (> 5.0)1 | |
Or renal replacement therapy1 | ||||||
CNS | HE grade | None | I | II | III1 | IV1 |
Coagulation | INR | < 1.1 | ≥ 1.1 to 1.25 | ≥ 1.25 to < 1.5 | ≥ 1.5 to < 2.5 | ≥ 2.5 or platlets < 201 |
Circulation | MAP (mmHg) | ≥ 70 | < 70 | Dopamine ≤ 51 | Dopamine > 51 | Dopamine > 15 |
Dobutamine | Epinephrine ≤ 0.11 | Epinephrine > 0.1 | ||||
Terlipressin1 | Norepinephrine ≤ 0.11 | Norepinephrine > 0.11 | ||||
Lungs | PaO2/FiO2 | > 400 | > 300 to ≤ 400 | > 200 to ≤ 300 | > 100 to ≤ 2001 | ≤ 1001 |
SpO2/FiO2 | > 512 | > 357 to ≤ 512 | > 214 to < 357 | > 89 to ≤ 2141 | ≤ 891 |
Indicates the limit for the definition of organ failure. HE: Hepatic encephalopathy; MAP: Mean arterial pressure; PaO2: Arterial oxygen tension; FiO2: Fraction of inspired oxygen; SpO2: Peripheral capillary oxygen saturation.