Fig. 3.

High levels of nitric oxide induced activity and expression of redox proteins. Trx activity (A) and Trx1 protein expression (B), Grx activity (C) and Grx1 protein expression (D), TrxR (E) and TXNIP (F) protein expression increased in NOS-3 overexpressing cells compared to cells transfected with the empty vector. Data are presented as mean±SEM (n=3 independent experiments) and the groups labeled with “a” were significantly statistical (p≤0.05) versus the corresponding control group. Representative Western blotting images are shown.