Table 4.

Multivariate regression analysis for FMD and TR jet velocity

	Parameter estimate	SE	95% CI	P value
Multivariate linear regression analysis TR jet velocity (cm/s) (n = 73)
ln(plasma free Hb)	13.9	6.1	1.8 to 26.1	.025
Transfusion status (CT)	−12.5	5.8	−24.1 to −0.8	.037
Height	0.55	0.27	0.01 to 1.10	.045
LDH	0.01	0.01	−0.002 to 0.03	.102
Hct	−1.36	0.98	−3.3 to 0.6	.167
Multivariate linear regression analysis FMD (%) (n = 61)
ln(plasma free Hb)	−1.21	0.43	−2.1 to −0.4	.007
Height	−0.05	0.02	−0.1 to −0.01	.03
Hematocrit	0.11	0.07	−0.03 to 0.26	.12
Sex (female)	0.53	0.33	−0.13 to 1.18	.11
HbS%	0.001	0.01	−0.02 to 0.03	.88

Univariate candidate variables were input to multivariate linear regression first by stepwise analysis and second using the method of least squares analysis. The results provide insight into the most significant variables that predict TR jet velocity and flow-mediated dilation of the brachial artery. Bold P values indicate significant differences, P < 0.05.