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Influence of CFE parameters C, E and H on simulated pathology in five regions-of-interest. Plots are colour-coded by AFROC area under the curve (AUC). All plots were generated with SNR = 1 and a connectivity-based smoothing kernel of 10 mm FWHM. As indicated by the red squares, values H = 3, E = 2, C = 0.5 achieve good results for all regions-of-interest.
