Table II.

Neopeptides identified in OA SF. Neopeptides shown were identified by Mascot with a significant score in ≥2 SF but no normal donors together with a minimum ion score of 20 Amino acids shown in red correspond to the end of the neopeptide corresponding to a potential cleavage site. Amino acids before and after represent those preceding the peptide sequence and following the peptide sequence in the protein

* denotes found in previous interleukin-1 cartilage explant study.

† denotes found in previous a disintegrin with thrombospondin motifs (ADAMTS4) study⁵⁰.

‡ denotes found in previous matrix metalloproteinase 3 (MMP3) study⁵⁰.

§ denotes previously identified in matrix-assisted laser desorption ionisation study¹³.

‖ denotes previously identified in equine tendon study²².