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. 2015 Jun 23;290(32):19544–19557. doi: 10.1074/jbc.M115.638924

TABLE 1.

The PPARγ agonist RGZ and signaling through the GPR40 pathway function synergistically to induce PPARγ-regulated genes

siRNA target p values for RGZ and siRNA silencing interactions
CD36 CYP1A1 FABP4 All three genes combined
p38 MAPK <0.001 0.04 0.02 <0.001
GPR40 0.04 0.02 0.11 0.03
PGC1α 0.005 0.18 0.006 0.03
SIRT1 <0.001 0.09 0.06 <0.001
EP300 <0.001 0.007 <0.001 0.008
All siRNA silencing combined <0.001 0.001 <0.001 <0.001