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. 2015 Aug 7;5:12898. doi: 10.1038/srep12898

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MSC were incubated with different doses of Ex-4 for 24 h. Their viability was assessed with MTT, and the activation of the PI3K/Akt pathway was evaluated by western blotting. (A) Ex-4 had no toxic effects on MSC. (B) Ex-4 activated Akt in a dose-dependent manner. *P < 0.05 vs. control group, ^#P < 0.05 vs. Ex-4 group; LY, LY294002.