Table 3.
Histopathological findings in FNA and FNB groups according to needle passes
| FNA group: 1st pass only versus FNB group: 1st pass only |
FNA group: all passes versus FNB group: 1st pass only |
FNA group: all passes versus FNB group: all passes |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| FNA | FNB | p | FNA | FNB | p | FNA | FNB | p | |
| N of cells (C/SA) | 0.04 | 0.09 | 0.03 | ||||||
| Fair < 100 | 10 (20%) | 2 (4%) | 6 (12%) | 2 (4%) | 6 (12%) | 0 (0) | |||
| Good 100 to 1000 | 13 (26%) | 14 (28%) | 20 (40%) | 14 (28%) | 20 (40%) | 24 (48%) | |||
| Excellent > 1000 | 27 (54%) | 34 (68%) | 24 (48%) | 34 (68%) | 24 (48%) | 26 (52%) | |||
| Microfragments | |||||||||
| Present | 9 (18%) | 30 (60%) | < 0.001 | 16 (32%) | 30 (60%) | 0.008 | 16 (32%) | 38 (76%) | < 0.001 |
| Mean number ± SD | 1.56 ± 0.73 | 2.53 ± 2.7 | 0.29 | 0.7 ± 1.3 | 1.5 ± 2.4 | 0.57 | 0.7 ± 1.3 | 2.3 ± 2.0 | 0.10 |
| Mean size ± SD | 1.54 ± 0.68 | 1.6 ± 1.0 | 0.88 | 0.5 ± 0.8 | 1.0 ± 1.1 | 0.53 | 0.5 ± 0.8 | 1.2 ± 1.0 | 0.58 |
| Tumoral cells (SA/S) | 0.30 | 0.17 | 0.70 | ||||||
| Absent | 15 (30%) | 9 (18%) | 7 (14%) | 9 (18%) | 7 (14%) | 5 (10%) | |||
| Minimal < 25% | 22 (44%) | 24 (48%) | 32 (64%) | 24 (48%) | 32 (64%) | 33 (66%) | |||
| Moderate 25–50% | 11 (22%) | 11 (22%) | 10 (20%) | 11 (22%) | 10 (20%) | 9 (18%) | |||
| Significant > 50% | 2 (4%) | 6 (12%) | 1 (2%) | 6 (12%) | 1 (2%) | 3 (6%) | |||
| Blood content (SA/S) | 0.17 | 0.001 | 0.06 | ||||||
| Absent | 9 (18%) | 4 (8%) | 2 (4%) | 4 (8%) | 2 (4%) | 0 | |||
| Minimal <25% | 24 (48%) | 19 (38%) | 28 (56%) | 19 (38%) | 28 (56%) | 22 (44%) | |||
| Moderate 25–50% | 8 (16%) | 11 (22%) | 18 (36%) | 11 (22%) | 18 (36%) | 19 (38%) | |||
| Significant >50% | 9 (18%) | 16 (32%) | 2 (4%) | 16 (32%) | 2 (4%) | 9 (18%) | |||
| Digestive contamination (SA/S) | 0.6 | 0.41 | 0.43 | ||||||
| No contamination | 25 (50%) | 23 (46%) | 21 (42%) | 23 (46%) | 21 (42%) | 15 (30%) | |||
| Contamination <25% | 23 (46%) | 22 (44%) | 27 (54%) | 22 (44%) | 27 (54%) | 33 (66%) | |||
| Contamination 25–50% | 2 (4%) | 5 (10%) | 2 (4%) | 5 (10%) | 2 (4%) | 2 (4%) | |||
| Necrotic tissue (SA/S) | 0.42 | 0.005 | 0.13 | ||||||
| Absent | 14 (28%) | 19 (38%) | 5 (10%) | 19 (38%) | 5 (10%) | 9 (18%) | |||
| Minimal < 25% | 23 (46%) | 23 (46%) | 34 (68%) | 23 (46%) | 34 (68%) | 37 (74%) | |||
| Moderate 25–50% | 7 (14%) | 6 (12%) | 10 (20%) | 6 (12%) | 10 (20%) | 3 (6%) | |||
| Significant > 50% | 6 (12%) | 2 (4%) | 1 (2%) | 2 (4%) | 1 (2%) | 1 (2%) | |||
| Inadequate for analysis | 13 (26%) | 3 (6%) | 0.001 | 5 (10%) | 3 (6%) | 0.15 | 5 (10%) | 0 (0%) | 0.02 |
C/SA: cells per surface area; FNA: fine needle aspiration; FNB: fine needle biopsy; NS: not significant; SA/S: surface area per slide; SD: standard deviation