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. 2015 Aug 7;5:12895. doi: 10.1038/srep12895

Figure 1. Male mice show an accumulation of cTECs with age that is not due to enhanced cell proliferation.

Figure 1

(a) Thymic cell populations in mice aged from 1 to 12 months. The gating strategy is depicted in Supplementary Figure S1c. (b) Percentage of TEC populations in 6 month-old mice, mean percentage of Ki-67+ cells at 4–5 months of age, and half-life (in weeks) of H2B-GFP+ TECs calculated using one phase decay nonlinear regression. (c) Percentages of Ki-67+ TECs in 4 to 5 month-old mice. (d) H2B-GFP dilution in adult mice during a chase period of 16 weeks. (e) Correlation (Pearson) between different features of TEC populations in 6 month-old mice. Each dot represents onemouse.