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. 2015 Aug 7;2:49. doi: 10.3389/fmed.2015.00049

Figure 1.

Figure 1

Overview of “big events” in pathophysiology of BPD. The three major programs that are active during the course of BPD are lung development, injury, and repair. The major injuries are from oxygen and ventilation-associated inflammation. The time line for the fetus and infant occurs over months to years, which contrasts to studies in term rodent models.