Table 3. Reduction of function of five Wnt-regulated genes alters terminal seam cell number.
| Strain | n | Average Adult Seam Cell No. | Range |
|---|---|---|---|
| control(RNAi) | 246 | 15.6 | 13–16 |
| cdk-4(RNAi) | 35 | 11.9a | 7–16 |
| cki-1(RNAi) | 38 | 20.6a | 17–26 |
| kin-10(RNAi) | 42 | 23.9a | 16–36 |
| mlt-11(RNAi) | 43 | 10.5a | 7–13 |
| nhr-23(RNAi) | 53 | 13.3a | 9–16 |
All animals contain rrf-3(pk1426) and seam cell–specific marker grd-10::gfp; GFP+ cells were counted in young adult worms. The number of adult seam cells per side in control RNAi (feeding vector alone) and animals treated with RNAi against the indicated Wnt regulated genes is shown.
a
P ≤ 0.001 (unpaired t-test) compared to control (RNAi).