Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 6;12(108):20150312. doi: 10.1098/rsif.2015.0312

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

PMC Copyright notice

Figure 1. — Prototypical genetic network modules. The prototypical input–output system (a) with total DNA (), mRNA and protein () is shown. Dimerization of monomeric input transcription factor (TF) () and output TF () has been considered as well as operator-binding and lumped transcription, translation and degradation. The input–output ‘module’ acts as a building block for modelling larger networks. For the case of multiple operators (b), the system also includes the total additional TF binding sites () and the total protein concentration also includes the TF bound to the second operator. In (b), the additional regulatory element is part of a second promoter, but the models and methodology are also applicable when additional elements regulate expression of the same gene. (Online version in colour.)

Inline graphic — Prototypical genetic network modules. The prototypical input–output system (a) with total DNA (), mRNA and protein () is shown. Dimerization of monomeric input transcription factor (TF) () and output TF () has been considered as well as operator-binding and lumped transcription, translation and degradation. The input–output ‘module’ acts as a building block for modelling larger networks. For the case of multiple operators (b), the system also includes the total additional TF binding sites () and the total protein concentration also includes the TF bound to the second operator. In (b), the additional regulatory element is part of a second promoter, but the models and methodology are also applicable when additional elements regulate expression of the same gene. (Online version in colour.)