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Selectivity and specificity of PEG-FOL-Cu2S-DOX towards cancer cells. a) In vitro selective tumoricidal activity of PEG-FOL-Cu2S-DOX at different concentrations (0.01 – 1mg/mL) in comparison to free DOX post 24 h incubation with cells. b) Cancer specific cellular entry of PEG-FOL-Cu2S-DOX NCs. The specificity of NC entry only into cancer cell (Gl-1) could be attributed to the folate targeting.
