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. 2015 Aug 7;13:257. doi: 10.1186/s12967-015-0622-x

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© Castañón et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — OS depending on the presence of LM at onset or during disease curse. a At onset, LM presence seems to be a poor prognosis factor detecting an OS of 10 months when LM are present (n = 40) compared to 21 months when no liver metastases are diagnosed at the moment of stage IV NSCLC diagnosis (n = 196). b A better overall survival is achieved in stage IV NSCLC patients who never present liver involvement (n = 144) compared to those patients in whom LM are present during the course of the disease (n = 86).