Fig. 1.

Nlr expression in primary Schwann cells, motor neurons, sensory neurons, peritoneal macrophages, and the sciatic nerve. a Nlr expression relative to the two most stable housekeeping genes out of five in the different primary cells, as determined by RT-qPCR. Note the different Y-axis scales used in the upper panel of each cell type. In the lower panel, the Y-axis is set to the same scale. In the graphs, the pooled data of three independent experiments is shown. b Ranking of Nlrs according to their relative expression levels in different PNS cell types as well as in the sciatic nerve, based on three to five independent experiments. − absent; +/− borderline detectable; +, ++, +++, ++++, +++++ indicate low to very strong expression