Figure 3.

CuH-catalyzed hydroamination of styrenes for the formation of chiral secondary amines. ^aYields are determined using GC with dodecane as an internal standard; unless otherwise noted, CuH solution used in this study was prepared in a nitrogen-filled glovebox. ^bIsolated yields on 1 mmol scale (average of two runs); enantiomeric excesses (ee) were determined by chiral HPLC analysis; see Supporting Information for experimental details. ^cThree equivalents of HSi(OEt)₂Me was used, and 10e was added over 1.5 h.