Table 1. Scope of Amine Transfer Reagents in Hydroamination Reactions^a.

^aReactions performed on 1 mmol scale for 17a–d and 0.5 mmol scale for 17e–l. Isolated yields are reported (average of two runs). Enantiomeric excesses (ee) were determined by chiral HPLC analysis or ¹H NMR analysis. Diastereomeric ratios (dr) were determined by ¹H NMR or gas chromatography analysis.

^bToluene was used as the solvent, and amine transfer reagent with a pivolate leaving group was used as the substrate (see Supporting Information).