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. 2015 Aug 8;12:122. doi: 10.1186/s12985-015-0353-x

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© Susta et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Macroscopic pictures illustrating lesions in rZJ1-IL2 and rZJ1-GFP-infected chickens. Panel a: eyelid; 4-week-old White Leghorn chicken infected with rZJ1-IL2, day 4 pi. Severe conjunctivitis characterized by hemorrhages, edema and congestion of the upper and lower eyelid. Panel b: comb; 4-week-old White Leghorn chickens infected with rZJ1-IL2, day 6 pi. Severe comb hemorrhages, edema, and cyanosis. Panel c and d: duodenal loop; 4-week-old White Leghorn chicken infected with rZJ1-GFP (c) and rZJ1-IL2 (d), day 4 pi. Note absence of intestinal hemorrhages in ZJ1-IL2-infected birds, compared to ZJ1-GFP-infected birds