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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Comput Neurosci. 2015 Apr 3;38(3):539–558. doi: 10.1007/s10827-015-0553-9

Fig. 8. Conductances can either increase or reduce the PRC minimum phase response.

Fig. 8

(a) Histogram of sensitivities of minimum phase response of PRC families to Na. (b) Example of a five-member PRC family with minimum phase responses that decrease with increasing Na. All PRC family members are shaded from light to dark, with the lightest PRC having the lowest Na value and the darkest PRC having the highest Na value. Na values of the model neurons corresponding to each PRC are given by multiplying the integer M by 100 mS/cm2. The spontaneous activity patterns of the model neurons with the smallest (M=1, top) and largest (M=5, bottom) Na values in the family are shown below the PRCs. (c) Example of a five-member PRC family with minimum phase responses that increase with increasing Na. (d) Histogram of sensitivities of minimum phase responses of PRC families to leak. (e) Example of a five-member PRC family with minimum phase responses that decrease with increasing leak. leak values of the model neurons corresponding to each PRC are given by multiplying the integer M by 0.01 mS/cm2. The spontaneous activity patterns of the model neurons with the smallest (M=1, top) and largest (M=5, bottom) maximal leak values in the family are shown below the PRCs. (f) Example of a five-member PRC family with minimum phase responses that increase with increasing leak