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. Author manuscript; available in PMC: 2015 Aug 7.
Published in final edited form as: J Immunol. 2009 Nov 13;183(11):7268–7277. doi: 10.4049/jimmunol.0901957

Figure 4. P4c-Mal induces long term immunity that is boostable by challenge with live sporozoites.

Figure 4

(A) Groups (n=5) mice received three doses of P4c-Mal or saline at 0, 2 and 4 wks. A group was challenged with live sporozoites either 14 days, or 1, 3 or 6 months later. (B) Groups (n=5) mice received three doses of P4c-Mal or saline at 0, 2 and 4 wks. All mice that received P4c-Mal were challenged with live sporozoites two weeks post 3rd dose of vaccine. All mice survived challenge. A group (n=5) of vaccinated and challenged mice or mice receiving saline only were challenged a second time either 1, 3, 6, 9 or 15 months later with live sporozoites.