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. 2015 Aug 1;142(15):2665–2677. doi: 10.1242/dev.122473

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© 2015. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Basally migrating RINs in apical regions of the retina appear bipolar. (A) Selected frames from a movie of a Ptf1a:DsRed retina starting at ∼45 hpf. Images are shown as maximum intensity z-projections. At 0 min, tips of RIN apical processes (arrowheads) are seen to be attached to the apical surface of the retina (top dashed green line). At 540 min, when dACs (blue arrows) can be seen to separate from the main body of RINs in the middle of the retina, multipolar RINs, presumably HCs, can be seen migrating towards the OPL (orange arrows). (B) Selected time frames from a movie of Ptf1a:DsRed cells transplanted into a WT embryo starting at ∼45 hpf. Blue arrowheads indicate a RIN that transitions from bipolar to multipolar morphology. AS, apical surface; BS, basal surface.