Table 1.
n | Mean age at death (years) | APOE ε4 % (+/−)a | DP freq (%) | NP freq (%) | |
---|---|---|---|---|---|
CTE (all) | 114 | 60 | 33 % (27/55) | 52 | 36 |
Stage I | 13 | 35 | 33 % (3/6) | 15 | 0 |
Stage II | 30 | 52 | 32 % (7/15) | 33 | 20 |
Stage III | 34 | 62 | 23 % (6/20) | 44 | 27 |
Stage IV | 37 | 75 | 44 % (11/14) | 87 | 70 |
AD | 319 | 80 | 59 % (13/9) | 84 | 100 |
CTE Chronic traumatic encephalopathy, DP diffuse plaques, NP neuritic plaques, AD Alzheimer’s disease
% of both ε4 hetereozytes and homozygotes out of those cases with genotypes (n = 82)