Compared with vehicle (V, open bars), paclitaxel (P, black bars) led to significant nitration of the glutamate transporter GLT-1 (A) and GS (B) in spinal cord tissues, events attenuated in rats treated with IB-MECA (0.1 mg/kg/d, D0–15; gray bars). Representative blots are shown. Results are expressed as mean ± SD for n=5 rats and analyzed by one-way ANOVA with Dunnett’s comparisons. *P<0.05 vs. Vehicle; †P<0.05 vs. Paclitaxel