FIG. 7.

Potential clinical applications for the multilayer scaffold system. (A) Anatomical drawings of juxtaposed bone and cartilage in the hip (coronal plane view, left) and knee (anterior view, right) joints. (B) Photographs of a cylindrical osteochondral defect in a model of a human femoral head (left) and insertion of the multilayer PLG scaffold in the defect model (right). (C) Proposed workflow of future clinical applications of these scaffold systems. A three-dimensional (3D) model of a human femur reconstructed from CT imaging (left) was used to design a customized scaffold mold in SolidWorks (middle), which was then 3D printed at 1:8 anatomical scale (right). Standard US pennies are shown for size comparison. Color images available online at www.liebertpub.com/tea