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PFTβ does not change the frequency or timing of tumor development in p53+/− mice. p53+/− were injected i.p. with PFTβ (25 mg/kg, n = 60) or vehicle (n = 55) 30 min prior to 4 Gy TBI. Mouse survival, and sarcoma and lymphoma development (% of mice with tumors at different time points) were assessed.
