Table 3. Number of cases and controls with potential risk factors for KA, univariate Odds Ratios (OR) controlled for age, sex, village and adjusted OR obtained in final multivariate model.
Cases | Controls | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|---|
(n = 35) | (n = 139) | OR a | 95% C.I. | p | OR b | 95%CI | p | |
Contact with known endemic areas | 9 | 40 | 0.73 | 0.27–1.87 | 0.524 | |||
VL case in family | 15 | 26 | 3.21 | 1.26–8.23 | 0.014* | |||
VL case in close d neighborhood | 35 | 52 | 116 e | 6.90–1915.42 | 0.000*** | |||
DAT-positive in family | 20 c | 47 | 2.36 | 0.96–5.89 | 0.061 | |||
Monthly income (per 1000 NRS) | 1.11 | 1.09–1.22 | 0.035* | |||||
Occupation | 0.421 | |||||||
Agriculture (ref) | 4 | 19 | 1 | - | - | |||
Daily labour | 7 | 12 | 2.72 | 0.58–14.27 | 0.211 | |||
House wife | 8 | 24 | 2.09 | 0.46–11.34 | 0.357 | |||
Student | 14 | 77 | 0.81 | 0.16–4.99 | 0.809 | |||
Other | 2 | 7 | - | - | - | |||
House type | 0.096 | |||||||
Thatched (ref) | 11 | 52 | 1 | - | - | |||
Mud (Kaccha) | 17 | 61 | 2.14 | 0.63–8.73 | 0.246 | |||
Semi-Pakka (Mixed cement) | 6 | 14 | 5.59 | 1.17–29.31 | 0.033* | |||
Wood | 1 | 12 | - | - | - | |||
Sleeping on the ground | 16 | 34 | 3.60 | 1.23–10.72 | 0.020* | 5.65 | 1.12–30.43 | 0.035 |
Sleeping under bed net | 6 | 33 | 0.60 | 0.19–1.71 | 0.369 | |||
Owning domestic animal(s) | 29 | 104 | 0.60 | 0.55–1.09 | 0.274 | |||
Cow dung in front of house | 21 | 42 | 4.01 | 1.72–9.65 | 0.001** | 4.70 | 1.21–20.06 | < 0.001 |
Vegetation around house | 11 | 39 | 0.86 | 0.19–3.21 | 0.837 | |||
Contact with river | 14 | 27 | 2.92 | 0.85–10.25 | 0.088 | |||
Distance house- river (per km) | 0.06 | 0.002–0.53 | 0.010* | 0.06 | 0.001–0.92 | 0.001 |
aAdjusted for age, sex, village in separate logistic regression models.
bAdjusted OR obtained in final multivariate conditional logistic regression model.
cn = 34.
dWithin 100 meter from house.
eOR = positive infinity. Values shown were computed for 34,9999 exposed cases instead of 35.