Table 3. Biochemistry and renal function parameters.
SHAM (n = 10) | UNX (n = 10) | AV (n = 9) | UNX +AV (n = 15) | |
---|---|---|---|---|
Rat BNP-45 (ng/ml) | 0.14±0.02 | 0.17±0.03 | 0.23±0.11 | 0.25±0.06 |
sCr(mg/L) | 4.68±0.87 | 5.56±0.48 * | 4.43±0.63 † | 6.06±0.75 * ‡ |
Cys-c(μg/ml) | 1.51±0.19 | 2.66±0.63 * | 1.80±0.47 | 2.91±0.66 * ‡ |
GFR(ml/min/kg) | 0.079±0.041 | 0.045±0.015 | 0.093±0.099 | 0.028±0.010 * |
ERPF(ml/min/kg) | 1.672±0.935 | 0.871±0.712 | 4.093±3.629 † | 0.799±0.318 ‡ |
RBF(ml/min/kg) | 2.944±1.727 | 1.468±1.200 | 6.792±5.795 † | 1.326±0.512 ‡ |
RVR(mmHg/ ml/min/kg) | 45.275±24.851 | 89.681±35.561 * | 32.853±29.827 † | 74.259±26.763 ‡ |
FENa | 0.087±0.055 | 0.120±0.075 | 0.535±0.675 * | 0.263±0.107 * |
UV(μl/min) | 12.670±9.460 | 6.013±2.151 | 29.209±33.573 † | 11.339±3.485 |
24-h Albumiuria (μg) | 155.49±115.25 | 113.35±127.44 | 167.52±100.34 | 291.01±183.13 |
Values are mean±SD. BNP-45, rat brain natriuretic peptide-45; sCr, plasma creatinine; Cys-c, Cystatin C; GFR, glomerular filtration rate; ERPF, effective renal plasma flow; RBF, renal blood flow; RVR, renal vascular resistance; FENa, fractional excretion of sodium; UV, urine volume
*p<0.05 vs. Sham
†p<0.05 vs. UNX
‡ p<0.05 vs. AV.