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. 2015 Aug 7;10(8):e0134579. doi: 10.1371/journal.pone.0134579

Table 3. Biochemistry and renal function parameters.

SHAM (n = 10) UNX (n = 10) AV (n = 9) UNX +AV (n = 15)
Rat BNP-45 (ng/ml) 0.14±0.02 0.17±0.03 0.23±0.11 0.25±0.06
sCr(mg/L) 4.68±0.87 5.56±0.48 * 4.43±0.63 6.06±0.75 *
Cys-c(μg/ml) 1.51±0.19 2.66±0.63 * 1.80±0.47 2.91±0.66 *
GFR(ml/min/kg) 0.079±0.041 0.045±0.015 0.093±0.099 0.028±0.010 *
ERPF(ml/min/kg) 1.672±0.935 0.871±0.712 4.093±3.629 0.799±0.318
RBF(ml/min/kg) 2.944±1.727 1.468±1.200 6.792±5.795 1.326±0.512
RVR(mmHg/ ml/min/kg) 45.275±24.851 89.681±35.561 * 32.853±29.827 74.259±26.763
FENa 0.087±0.055 0.120±0.075 0.535±0.675 * 0.263±0.107 *
UV(μl/min) 12.670±9.460 6.013±2.151 29.209±33.573 11.339±3.485
24-h Albumiuria (μg) 155.49±115.25 113.35±127.44 167.52±100.34 291.01±183.13

Values are mean±SD. BNP-45, rat brain natriuretic peptide-45; sCr, plasma creatinine; Cys-c, Cystatin C; GFR, glomerular filtration rate; ERPF, effective renal plasma flow; RBF, renal blood flow; RVR, renal vascular resistance; FENa, fractional excretion of sodium; UV, urine volume

*p<0.05 vs. Sham

†p<0.05 vs. UNX

‡ p<0.05 vs. AV.