Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Aug 7;10(8):e0133167. doi: 10.1371/journal.pone.0133167

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Jujo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Fig 2 — A to C show pulmonary muscular arteries from Case 17 with intimal fibrotic changes and moderate medial thickening. (A) Modified Masson-Goldner stain (Elastica Masson stain) shows the complicated arrangement of collagen (green), elastin (dark-purple) and spindle cells (red) within the intima. (B) Numerous α-smooth muscle actin (SMA) positive cells are recognized in the thickened intima and media in the artery. (C) Factor VIII is negative within the intima and media. Only endothelial cells are positive for factor VIII. D to F show pulmonary venules from Case 10 with intimal alterations. (D) Modified Masson-Goldner stain show that the neointima of venopathy is rich in collagen (green). (E) α-SMA-positive cells can be seen in the media and thin intima; however, the number of the cells is less than that seen in pulmonary arteriopathy. (F) Factor VIII is only positive in the endothelial cells. (Scale bars show 100 μm)