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. 2015 Jul 31;9:3989–4104. doi: 10.2147/DDDT.S85426

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© 2015 He et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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UA increased serum SOD level and decreased serum MDA level in liver fibrotic rats.

Notes: Rats were administered with 1% DMN dissolved in saline (1 mL/kg body weight) by intraperitoneal injection for 3 consecutive days per week for 4 weeks to induce liver fibrosis. Bar graphs showing the serum level of SOD (A) and MDA (B) in rats received treatment of vehicle control, DMN alone, DMN +20 mg/kg UA, and DMN +40 mg/kg UA. Data are expressed as mean ± SD (n=5). ***P<0.001.

Abbreviations: UA, ursolic acid; SOD, superoxide dismutase; MDA, maleic dialdehyde; DMN, dimethylnitrosamine; SD, standard deviation.