Table 1.
Participants’ clinical data
| Participant | GMFCSa | IQb | Preferred hand | Hand with contracture | Diagnosis | MRI examination |
|---|---|---|---|---|---|---|
| CP1 | 2 | 71 | L | NA | Leg-dominated bilateral spastic CP | No examination |
| CP2 | 1 | 62 | L | NA | Dyskinetic CP | Age-normal image of neurocranium |
| CP3 | 3 | 81 | L | NA | Leg-dominated bilateral spastic CP | Age-normal image of neurocranium |
| CP4 | 2 | NAss | R | NA | Leg-dominated bilateral spastic CP | Age-normal image of neurocranium |
| CP5 | 1 | 71 | R | L | Unilateral spastic CP | Large cystic defect on the right temporo-fronto-parietal area with discrete circumjacent gliosis, consistent with ischemia |
| CP6 | 1 | 71 | L | R | Unilateral spastic CP | No examination |
| CP7 | 1 | 74 | R | NA | Hypotone CP | Brain parenchyma normal to the age |
| CP8 | 1 | 92 | R | L | Unilateral spastic CP | No report possible due to movement in the scanner |
| CP9 | 2 | 79 | L | NA | Leg-dominated bilateral spastic CP | Periventricular leukomalacia consistent with fetal hypoxic brain damage |
| CP10 | 1 | NAss | L | R | Arm-dominated unilateral spastic CP | Large lesion in the left hemisphere covering motor cortical areas |
| GRMCD1 | 2 | 81 | R | NA | Global retardation | No indication of intracranial expansion, ischemia, or bleeding |
| GRMCD2 | 1 | 79 | R | NA | Developmental retardation | Asymmetry of the posterior horn. Myelination defect |
| GRMCD3 | 1 | 101 | L | NA | Neurofibromatosis | Large pineal gland cyst; no compression of neighboring structures. Lesion in the front part of the midbrain and in Globus Pallidus, both sides |
| GRMCD4 | 1 | 71 | R | NA | Global retardation | Age-normal image of neurocranium |
| GRMCD5 | 1 | 94 | L | NA | Global retardation | Age-normal image of neurocranium |
| GRMCD6 | 1 | 58 | R | NA | Global retardation | No indication of expansion or bleeding, but detailed examination not possible due to movement in the scanner |
| GRMCD7 | 1 | 81 | R | NA | Fragile X syndrome | Age-normal image of neurocranium |
| GRMCD8 | 1 | 79 | R | NA | Global retardation | No examination |
Notes:
a
Calculated according to the GMFCS.22
b
IQ is calculated according to the German version of the Wechsler Intelligence Scale, Hamburg Wechsler Intelligence Scale for Children (HAWIK-IV).23
Abbreviations: GMFCS, Gross Motor Function Classification System; IQ, intelligence quotient; MRI, magnetic resonance imaging; CP, cerebral palsy; GRMCD, global retardation and movement coordination disorder; L, left; R, right; NA, not applicable; NAss, not assessed.