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. 2015 Aug 7;10(8):e0134917. doi: 10.1371/journal.pone.0134917

Table 3. Emergency Department Visit Rates for Hypoglycemia and Hyperglycemic Crisis Among Adults With Treated Diabetes 2006–2011.

Characteristic Rate per 100 (95% CI) Percentage change P for Trend
2006 2007 2008 2009 2010 2011
Hypoglycemia
Crude rate, by age, y
    Overall 2.2 (2.0,2.4) 2.2 (2.0,2.3) 2.0 (1.8,2.1) 1.8 (1.6,1.9) 1.7 (1.6,1.8) 1.6 (1.5,1.7) -26.1 (-34.2,-18.1) <0.001
    18 to 44 2.7 (2.2,3.2) 3.2 (2.6,3.7) 3.0 (2.3,3.6) 2.1 (1.7,2.4) 2.2 (1.9,2.6) 2.2 (1.8,2.5) -19.3 (-38.1,-0.6) 0.10
    45 to 64 1.5 (1.4,1.7) 1.5 (1.3,1.6) 1.3 (1.1,1.4) 1.2 (1.1,1.3) 1.2 (1.1,1.4) 1.2 (1.1,1.2) -23.8 (-34.1,-13.6) 0.02
    65 to 74 2.0 (1.8,2.3) 1.8 (1.6,2.1) 1.8 (1.6,2.0) 1.7 (1.5,1.9) 1.6 (1.4,1.7) 1.4 (1.3,1.5) -30.9 (-41.8,-19.9) <0.001
    ≥75 3.6 (3.1,4.1) 3.8 (3.2,4.4) 3.7 (3.1,4.2) 3.2 (2.8,3.6) 2.7 (2.4,3.1) 2.8 (2.5,3.2) -22.1 (-36.4,-7.8) 0.01
Age-adjusted By sex a
    Overall 2.2 (2.0,2.3) 2.2 (2.0,2.4) 2.1 (1.9,2.2) 1.8 (1.6,1.9) 1.7 (1.6,1.9) 1.7 (1.5,1.8) -24.0 (-32.2,-15.7) 0.002
    Men 2.2 (1.9,2.4) 2.2 (1.9,2.4) 2.0 (1.8,2.3) 1.7 (1.5,1.8) 1.6 (1.4,1.8) 1.6 (1.4,1.7) -27.6 (-37.7,-17.6) 0.006
    Women 2.2 (1.9,2.4) 2.2 (2.0,2.5) 2.1 (1.8,2.3) 1.9 (1.7,2.1) 1.8 (1.7,2.0) 1.7 (1.6,1.9) -19.9 (-30.7,-9.1) 0.001
Hyperglycemic crisis
Crude rate, by age, y
    Overall 0.9 (0.8,1.0) 0.9 (0.8,1.0) 0.9 (0.8,1.0) 0.9 (0.8,1.0) 0.9 (0.8,1.0) 1.0 (0.9,1.1) 8.7 (-3.9,21.3) 0.38
    18 to 44 4.0 (3.3,4.7) 5.0 (4.1,6.0) 5.0 (4.0,6.0) 3.9 (3.3,4.6) 4.3 (3.5,5.0) 4.7 (4,5.4.0) 18.8 (-8.2,45.9) 0.72
    45 to 64 0.6 (0.5,0.6) 0.6 (0.5,0.6) 0.5 (0.5,0.6) 0.6 (0.5,0.6) 0.6 (0.6,0.7) 0.7 (0.6,0.7) 15.3 (0,30.5) 0.11
    65 to 74 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.3) 20.0 (4.7,35.3) 0.04
    ≥75 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.2 (0.2,0.2) 0.3 (0.2,0.3) 25.0 (-6.4,56.4) 0.08
Age-adjusted, by sex a
    Overall 0.9 (0.8,1.0) 1.1 (0.9,1.2) 1.1 (0.9,1.2) 0.9 (0.8,1.0) 1.0 (0.9,1.1) 1.1 (1,1.2.0) 18.5 (-1.3,38.3) 0.40
    Men 1.0 (0.8,1.1) 1.1 (0.9,1.3) 1.1 (0.8,1.3) 0.9 (0.7,1.0) 0.9 (0.8,1.1) 1.1 (0.9,1.3) 12.2 (-11.8,36.3) 0.90
    Women 0.9 (0.7,1.0) 1.0 (0.8,1.2) 1.1 (0.9,1.3) 1.0 (0.9,1.1) 1.0 (0.9,1.2) 1.1 (0.9,1.2) 24.1 (-1.0,49.3) 0.04

Abbreviations: ED, emergency department; CI, confidence interval.

Data from the Nationwide Emergency Department Sample and National Health Interview Survey (NHIS).

a Age-adjusted to population of adults with diabetes in 2010 based on NHIS, using age groups 18–44 years, 45–64 years, 65–74 years, and ≥75 years.

Boldface indicates statistical significance (p<0.05)