Table 2. Significant positive selection results in a minimum of two different tests.

Observed (Obs) F_ST with selection significance (highlighted P value<0.01) for the three continents (Africa, Asia and Europe) and for Europe and North Africa. Global cross-continental F_ST scores in the CEU, CHB, and YRI samples from the 1000 Genomes Selection Browser. Significant high and low FST values (extreme top 5% values of the distribution of F_ST values across the genome) are highlighted in bold. P values were calculated on the basis of higher rank scores in the genomic distribution. SPA scores for continental European, and North African allele gradients (highlighted in bold SPA scores above 99th percentile).

			Three Continents		Europe and North Africa		1000 Genomes Browser		Europe	North Africa
Genomic region	Position	SNP_ID	Obs FST	FST P-value	Obs FST	FST P-value	FST	P_values	SPA scores	SPA scores
1p13	109821307	rs583104	0.282	0.004	0.035	0.136	0.594	0.001	0.655	0.300
1p13	109821511	rs602633	0.293	0.002	0.034	0.151	0.592	0.001	0.596	0.312
1p13	109822166	rs599839	0.276	0.005	0.033	0.160	0.578	0.001	0.651	0.278
1q41	222839838	rs1053316	0.264	0.005	0.058	0.019	0.416	0.008	0.376	0.534
1q41	222844840	rs3008633	0.256	0.007	0.056	0.023	0.412	0.009	0.310	0.484
9p21	21920346	rs4977746	0.236	0.011	0.051	0.032	0.342	0.018	0.425	1.116
9p21	21930147	rs7864029	0.249	0.007	0.040	0.085	0.350	0.017	0.373	0.517
9p21	21931896	rs7869004	0.273	0.004	0.041	0.077	0.389	0.011	0.480	0.592
9p21	21946322	rs2811717	0.292	0.003	0.094	0.001	0.648	4.923E-04	0.310	0.624
9p21	22072301	rs9632884	0.143	0.117	0.071	0.008	0.327	0.021	2.075	0.358
9p21	22099568	rs1537371	0.128	0.159	0.071	0.008	0.292	0.029	2.046	0.435
9p21	22103813	rs1333042	0.130	0.152	0.070	0.008	0.287	0.031	2.043	0.464