Table 3.
Frequency of PAM50 intrinsic subtypes in independent series of primary breast cancer from Caucasian and Chinese patients
| Caucasian series | Chinese series | ||||
|---|---|---|---|---|---|
| Number of samples | 97 | 207 | 78 | 81 | 100 |
| Sample origin | Milan | Oxford | Shanghai | Taiwan | Singapore |
| GEO identifier | GSE59590 | GSE22219 | GSE59590 | GSE48390 | GSE36722 |
| PAM50 intrinsic subtype 24 (%) | |||||
| Basal-like | 15 (15) | 34 (16) | 10 (13) | 8 (10) | 8 (8) |
| ERBB2 | 12 (12) | 32 (15) | 17 (22) | 15 (19) | 17 (17) |
| Luminal A | 49 (51) | 88 (41) | 21 (27) | 15 (19) | 25 (25) |
| Luminal B | 15 (16) | 42 (19) | 23 (29) | 35 (43) | 38 (38) |
| Undetermined | 6 (6) | 20 (9) | 7 (9) | 8 (10) | 12 (12) |
| Luminal A/Luminal B ratio | 3.19 | 2.16 | 0.93 | 0.44 | 0.66 |
GEO, Gene Expression Omnibus.