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Biomarkers analysis. CEC and CEP cells did not change significantly (A), apoptotic circulating tumor cells increased over time (B), no significant change in platelet, endothelial, and monocyte microparticles (C–E) and platelet activation (F). CEC, circulating endothelia cells; CEP, circulating endothelial progenitor cells; CTC, circulating tumor cells; PMP, platelet microparticles; EMP, endothelial microparticles; MMP, monocyte microparticles.
